Skip to main content

Douxo Chlorhexidine Shampoo for Seborrhea in Dogs

  • Author:
  • Updated date:

Dr. Mark is a veterinarian. He has been working with dogs for more than 40 years.

Researchers recommend Douxo shampoo for sebborea in dogs. Here's why.

Researchers recommend Douxo shampoo for sebborea in dogs. Here's why.

The Best Seborrhea Shampoo for Dogs

Many dogs can be treated for seborrheic dermatitis to remove the crust, moisturize the skin, and keep the skin soft and dry until the next shampoo without having to use pills or supplements.

Shampooing is the most important step in treating seborrhea, but it's important to use the right kind.

The French company Douxo has developed a shampoo and mousse based on extracts from the plant Ophiopogon japonicus (better known as mondo grass or monkey grass) that is by far the best for treating seborrheic dermatitis in dogs.

Does Douxo S3 Work?

Dogs with chronic seborrhea were shampooed and treated with mousse every 48–72 hours; there was a 91% improvement by day 24. (1)

Seborrhea is difficult to treat in many cases, and many dogs develop dry skin during treatment or only improve after many months. Based on the quick response with Douxo, researchers recommend this product.

Scroll to Continue

Read More From Pethelpful

Douxo Chlorhexidine Mousse

Douxo mousse contains phytosphingosine, a kind of skin ceramide (fat) found in many kinds of human skin care products and often used to treat acne and eczema. (2) When tested on dogs, it kept the skin healthy and reduced inflammation, (3) so the shampoo and mousse should definitely be used together.

When to See a Vet About Seborrheic Dermatitis

Seborrhea is difficult to treat and there can be other things going on that need treatment. If this shampoo and mousse therapy do not work for your dog you need to consult your regular veterinarian and try an alternative.

Causes of Seborrheic Dermatitis in Dogs

Dogs or cats with greasy or flaky skin can have seborrhea. (4) This problem can either be genetic or secondary:

  • Hereditary (Schnauzer comedo syndrome and many others)
  • Nutritional (Zinc responsive, Vitamin A responsive, and fatty acid deficiency)
  • Parasites (Sarcoptic mange, Demodex, walking mange)
  • Allergies (food, inhalant, fleas, contact allergies)
  • Hormonal (hypothyroid, Cushings, and others)
  • Bacterial infection (pyoderma)
  • Fungal infection
  • Autoimmune disease
  • Cancer (cutaneous lymphoma)


  1. Gatellet, M, Ahman, S., Bruet, V., Cadot, P.M, Mueller, R.S., Noli, C., Nuttall, T., Ollivier, E., Blondel, T., and Savelli, N. Performance of a combined application of ophytrium-containing shampoo and mousse in dogs with sensitive skin: A European field trial. (2020), Abstracts. Vet. Dermatol., p 32.
  2. Colleen, D. (2020). What the Heck Is Phytosphingosine and What's It Doing in My Skincare Products?. Retrieved 25 July 2022, from
  3. Pin D, Bekrich M, Fantini O, Noel G, Vidémont E. An emulsion restores the skin barrier by decreasing the skin pH and inflammation in a canine experimental model. J Comp Pathol. 2014 Aug-Oct;151(2-3):244-54.
  4. Reese, Christine. Scaling or keratinization disorders in dogs (Proceedings),

This article is not meant to substitute for diagnosis, prognosis, treatment, prescription, or formal and individualized advice from your veterinarian. Animals exhibiting signs and symptoms of distress should be seen by a veterinarian immediately.

© 2022 Dr Mark

Related Articles